Yes. You will however need a screen to configure your computer to do this in the first instance.
Firstly, you need to have automatic login enabled on your Mac (go to System Preferences → Accounts → Login options and make sure Automatic login is set to 'enabled').
Then, open EigenD and click and hold the 'EigenD' dock icon until a menu appears, and select the 'Open at Login' option. EigenD will now load automatically when you start up your computer – you will need to allow time for your computer to boot up and the software to start, usually around 90 seconds, and your Eigenharp will be ready to play
(NB: the EigenBrowser application will not run without a screen).