The key layout of the alpha is totally awesome. I played it for about an hour and I can't stop thinking about it :-)
What I like about it is that just as with a guitar, the notes repeat themselves across the rows, so you get duplicate notes on the fingerboard, but you can use the most appropriate fingering based on where you are and what you want to play. You can also split the keyboard easily in different independent parts that have their own mode keys and octave keys. IIRC the split can be 1, 2, 3, 4 by default with larger and smaller areas depending on which instrument you find the most important.
The hardware is imho also better suited for the actual keys and fingerboard since you're typically playing it to the side of your head/torso, so you can glance at it easily even while blowing the breathpipe. The latter is something that's not that comfortable with the Pico.
What I also liked is that since it has a spike, it rests on the floor and you have no weight at all pulling down on your body. I wasn't able to try out the strap since the final version wasn't ready yet.
Hope this helps you, probably not, but you never know :-)